Endocrine Abstracts

Introduction: Multiple endocrine neoplasia type 1 (MEN-1) is a rare, autosomal dominant inherited disorder, characterized by a high predisposition to develop a wide spectrum of endocrine and nonendocrine tumors, mostly of parathyroids, endocrine pancreas, and anterior pituitary.Methods: Analysis of clinical and laboratory data, family history of multiple endocrine neoplasia.Results: A 19-year-old woman with autoimmune thyroiditis a...

Growth hormone deficiency (GHD) in children is a rare, aetiologically diverse condition that results in growth failure and short stature. Inadequate response to two different growth hormone stimulation tests (GHST) is required for the diagnosis of GHD. Macimorelin acetate, a potent, orally administered growth hormone (GH) secretagogue, is approved by the FDA and EMA for the diagnosis of adult GHD. Study AEZS-130-P01 is the first of two studies to investigate macimorelin acetat...